The colchicine is an important medicine for cancer. There are not only configurational problems of chiral carbon atom but the problems of configuration and conformation similar to the biphenyl derivatives. 秋水仙碱是医治癌症的重要药物,其结构中不仅存在手性碳原子的构型问题,也存在类似于联苯衍生物的构型和构象问题。
The research of the method of r/ s configuration mark of chiral carbon atom in the chiral molecule 手性分子中手性碳R/S构型标记方法的研究
The configuration and conformation between the two aromatic rings need to be determined after the configuartion of chiral carbon atom is determined. 确定了手性碳原子的构型,还必须确定两个芳环间的构型和构象。
An empirical rule for amidation of Type 2 amines ( in which the amino group attaches directly to the chiral carbon and only one H atom is at it) catalysis by lipase from candida antrarctica ( CAL) is proposed. 提出了2型胺(氨基直接与手性中心C连接,且手性中心C上只含有一个H)在CAL批肪酶催化作用下,酰胺化的异构选择规则。
There is a chiral carbon atom in the EAMP's molecule and it has been proved that the S-EAMP has higher biological activity than that of the D-EAMP. 它的分子结构中有一手性碳原子,大量研究结果证明其左旋光学异构体的生理活性比右旋异构体要高很多。
Study on about R/ S Mark Method of Configuration of Chiral Carbon Atom 手性碳C~构型的R/S标记方法探讨